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Cytolytic Activity of CAR T Cells and Maintenance of Their CD4+ Subset Is Critical for Optimal Antitumor Activity in Preclinical Solid Tumor Models

Marianna Csaplár, János Szöllősi, Stephen Gottschalk, György Vereb and Árpád Szöőr

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Enhancing the cellular uptake of cell penetrating peptides by decreasing the membrane dipole potential

Research carried out in collaboration between the Department of Biophysics

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Role of structural water molecules in slow inactivation of voltage-gated potassium channels

Role of structural water molecules in slow inactivation of voltage-gated potassium channels.

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Nuclear receptors (NR) compete for heterodimerization with RXR

Lina Fadel, György Vámosi and their collaborators from László Nagy’s lab in Debrecen...

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Mapping the dimerization and DNA binding of nuclear receptors in live cells by a novel microscopic method

Bálint Rehó, Gábor Mocsár, Lina Fadel, Péter Brázda, László Nagy, György Vámosi and

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The voltage-gated potassium channel KV1.3 as a therapeutic target for venom-derived peptides

 

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The activation gate controls steady-state inactivation and recovery from inactivation in Shaker

Tibor G Szanto, Florina Zakany, Gyorgy Panyi and their colleagues investigated the development of steady-state

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Determining the target of membrane sterols on voltage-gated potassium channels

Florina Zakany, Zoltan Varga and their colleagues investigated the effects...

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Endogenous DNA breaks were detected at RNA polymerase II promoters and are likely to contribute to genomic instability

Endogenous DNA breaks were detected at RNA polymerase II promoters and are likely to contribute to genomic instability

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Molecular background of the T lymphocyte’s Kv1.3 ion channel operation and targeting to the membrane.

Molecular background of the T lymphocyte’s Kv1.3 ion channel operation and targeting to the membrane.

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