News

Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion Centruroides villegasi

Kashmala Shakeel, Gyorgy Panyi, and their colleagues, in collaboration with Prof. Possani’s research group at UNAM, Mexico, are exploring peptide toxins that block specific potassium channels.

Role of CAR-T cell K+ channels in tumor infiltration and elimination

Vivien Jusztus, Árpád Szöőr and Péter Hajdu investigated the role of CAR-T cell potassium channels in tumor infiltration and elimination.

EGFR- HER2 Transactivation Viewed in Space and Time Through the Versatile Spectacles of Imaging Cytometry—Implications for Targeted Therapy

Investigations by László Ujlaky-Nagy, János Szöllősi, and György Vereb using complementary biophysical approaches on cellular model-systems may offer mechanistic insights into therapies targeting EGFR-HER2 interactions

Metal–organic framework nanoparticles carrying hypericin for anti-SARS-CoV-2 and antibacterial photodynamic therapy

Metal–organic framework nanoparticles carrying hypericin for anti-SARS-CoV-2 and antibacterial photodynamic therapy

The publication „Look Beyond Plasma Membrane Biophysics: Revealing Considerable Variability of the Dipole Potential Between Plasma and Organelle Membranes of Living Cells” by Mate Szabo, Bence Cs.Szabo, Kitti Kurtan, Zoltan Varga, Gyorgy Panyi, Peter Nagy, Florina Zakany and Tamas Kovacs can be read in full length in the International Journal of Molecular Sciences.

An easy-to-use method offer insights into the organization of cellular membranes of individual, intact living cells and can be used to identify affected organelles and therapeutic targets in diseases with alterations in membrane lipid composition.

Comparative Evaluation of Bleomycin- and Collagen-V-Induced Models of Systemic Sclerosis: Insights into Fibrosis and Autoimmunity for Translational Research

The research conducted by Lőrinc Nagy, Gábor Nagy, Tamás Juhász, Csaba Fillér, Gabriella Szűcs, Zoltán Szekanecz, György Vereb, Péter Antal-Szalmás, and Árpád Szöőr provides critical insights into the mechanisms underlying systemic sclerosis (SSc).

New opportunities in cancer therapy: CAR-NK cells against solid tumors

New opportunities in cancer therapy: CAR-NK cells against solid tumors

Dynamic P-glycoprotein Expression in Early and Late Memory States of Human CD8+ T Cells and the Protective Role of Ruxolitinib

Kipchumba Biwott, Zsolt Bacso, and their colleagues at the University of Debrecen studied the expression of the P-glycoprotein (Pgp/ABCB1) multidrug transporter in human CD8+ T lymphocytes during their differentiation.

Epigenetic modulation via the C-terminal tail of H2A.Z

Epigenetic modulation via the C-terminal tail of H2A.Z

Ghofrane Medyouni , Péter Hajdu and their colleagues in collaboration with  Cellular and Molecular Therapy group at the University of Debrecen studied the activity of potassium channels in CAR T cells.

Ghofrane Medyouni , Péter Hajdu and their colleagues in collaboration with Cellular and Molecular Therapy group at the University of Debrecen studied the activity of potassium channels in CAR T cells.