A kinetic trap mechanism underlies hHv1 inhibition by NZ-58
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Lamin A/C helps maintain the shape and internal organization of the cell nucleus and also influences how genes are regulated.
Chelidonine, the major alkaloid of Chelidonium majus L., has shown promising anticancer activity.
The development of new drug molecules targeting voltage-gated ion channels has declined in the last decade, highlighting the need for novel lead compounds with new mechanisms of action.
Vivien Jusztus, Péter Hajdu and his colleagues investigated the role of KCa3.1 ion channels in CAR-T cell migration and tumor cell elimination.
This study explores a new type of cancer immunotherapy based on CAR-NK cells—natural killer cells that are genetically engineered to better recognize and destroy cancer cells.
Laurdan and Di-4-ANEPPDHQ characterize molecular organization of the cell membrane at different depths.
Cancer is caused by mutations appearing in genes regulating the division and death of cells.
Changes in the activity of the voltage-gated potassium channel Kv1.3 have been linked to several autoimmune and neurological disorders.
László Mátyus, dean of the Faculty of General Medicine at the University of Debrecen, will continue to lead the Medical and Health Sciences Committee of the Hungarian Rectors’ Conference.