Functional role of Kv1.3 localization in chimeric antigen receptor T cells
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Ruxolitinib Modulates P-Glycoprotein Function, Delays T Cell Activation, and Impairs CCL19 Chemokine-Directed Migration in Human Cytotoxic T Lymphocytes
Fluorescence labeling causes global changes in antibody structure and dynamics through the hydrophobic effect
The plasma membrane is a dynamic structure surrounded by the extracellular matrix. Although stimulation of transmembrane proteins by soluble ligands takes place in this environment, its influence on receptor activation is usually overlooked.
Kashmala Shakeel, Gyorgy Panyi, and their colleagues, in collaboration with Prof. Possani’s research group at UNAM, Mexico, are exploring peptide toxins that block specific potassium channels.
Vivien Jusztus, Árpád Szöőr and Péter Hajdu investigated the role of CAR-T cell potassium channels in tumor infiltration and elimination.
Investigations by László Ujlaky-Nagy, János Szöllősi, and György Vereb using complementary biophysical approaches on cellular model-systems may offer mechanistic insights into therapies targeting EGFR-HER2 interactions
Metal–organic framework nanoparticles carrying hypericin for anti-SARS-CoV-2 and antibacterial photodynamic therapy
An easy-to-use method offer insights into the organization of cellular membranes of individual, intact living cells and can be used to identify affected organelles and therapeutic targets in diseases with alterations in membrane lipid composition.
The research conducted by Lőrinc Nagy, Gábor Nagy, Tamás Juhász, Csaba Fillér, Gabriella Szűcs, Zoltán Szekanecz, György Vereb, Péter Antal-Szalmás, and Árpád Szöőr provides critical insights into the mechanisms underlying systemic sclerosis (SSc).